Type: Package Package: NACHO Title: NanoString Quality Control Dashboard Version: 2.0.6.9000 Authors@R: c(person(given = "Mickaël", family = "Canouil", role = c("aut", "cre"), email = "pro@mickael.canouil.dev", comment = c(ORCID = "0000-0002-3396-4549")), person(given = "Roderick", family = "Slieker", role = "aut", email = "R.C.Slieker@lumc.nl", comment = c(ORCID = "0000-0003-0961-9152")), person(given = "Gerard", family = "Bouland", role = "aut", email = "G.A.Bouland@lumc.nl")) Description: NanoString nCounter data are gene expression assays where there is no need for the use of enzymes or amplification protocols and work with fluorescent barcodes (Geiss et al. (2018) ). Each barcode is assigned a messenger-RNA/micro-RNA (mRNA/miRNA) which after bonding with its target can be counted. As a result each count of a specific barcode represents the presence of its target mRNA/miRNA. 'NACHO' (NAnoString quality Control dasHbOard) is able to analyse the exported NanoString nCounter data and facilitates the user in performing a quality control. 'NACHO' does this by visualising quality control metrics, expression of control genes, principal components and sample specific size factors in an interactive web application. License: GPL-3 URL: https://github.com/mcanouil/NACHO/, https://m.canouil.dev/NACHO/ BugReports: https://github.com/mcanouil/NACHO/issues Depends: R (>= 3.6.0) Imports: utils, data.table, ggplot2 (>= 3.3.0), ggforce (>= 0.3.1), ggrepel (>= 0.8.1), knitr (>= 1.25), rmarkdown (>= 1.16), shiny (>= 1.4.0), shinyWidgets (>= 0.4.9) Suggests: roxygen2 (>= 7.2.0), testthat (>= 2.2.1), covr (>= 3.3.2), Biobase, GEOquery, limma VignetteBuilder: knitr Encoding: UTF-8 LazyData: true Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.0 SystemRequirements: pandoc (>= 1.14), pandoc-citeproc Config/testthat/edition: 3 Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev make libuv1-dev zlib1g-dev Repository: https://mcanouil.r-universe.dev Date/Publication: 2024-01-12 19:14:49 UTC RemoteUrl: https://github.com/mcanouil/NACHO RemoteRef: HEAD RemoteSha: 7c2b47df9c10e7d263101f20a81e017bbfefba1c NeedsCompilation: no Packaged: 2026-06-19 10:55:02 UTC; root Author: Mickaël Canouil [aut, cre] (ORCID: ), Roderick Slieker [aut] (ORCID: ), Gerard Bouland [aut] Maintainer: Mickaël Canouil